![]() ![]() The epigenetic factor LIN‐53 (RBBP4/7) associates with different chromatin‐regulating complexes to safeguard cell identities in Caenorhabditis elegans as well as mammals, and has a role in preventing memory loss and premature aging in humans. Chromatin factors could be involved in linking both aging aspects, as epigenetic mechanisms bridge regulation of different biological processes. However, to which degree lifespan and aspects of healthspan regulation might be linked is not well understood. Whether extension of lifespan provides an extended time without health deteriorations is an important issue for human aging.
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